Several pancreatic, gastric, lung, endometrial, cervical and ovarian cancers showed moderate to strong cytoplasmic staining. Remaining malignancies were negative.
CLEC4A (HGNC Symbol)
CD367, CLECSF6, DCIR, DDB27
C-type lectin domain family 4, member A (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in inflammatory and immune response. Multiple transcript variants encoding distinct isoforms have been identified for this gene. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]