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Cancer tissues showed weak to moderate staining in most cases. Thyroid cancers showed strong positivity. Breast and ovarian cancers were mainly negative.
GENE INFORMATION
Gene name
FRK (HGNC Symbol)
Synonyms
GTK, PTK5, RAK
Description
Fyn-related Src family tyrosine kinase (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth. [provided by RefSeq, Jul 2008]
Enzymes ENZYME proteins Transferases Kinases Tyr protein kinases SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)