Expression of ADTRP in cancer - Summary - The Human Protein Atlas

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ADTRP

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ADTRP
Gene description	Androgen-dependent TFPI-regulating protein
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Group enriched (hTCEpi, HUVEC TERT2, K-562, RPMI-8226, TIME, U-138 MG, U-266/84)
HPA (normal tissue):	Tissue enhanced (small intestine)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA048113
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA048113

GENE INFORMATION
Gene name	ADTRP (HGNC Symbol)
Synonyms	AIG1L, C6orf105, dJ413H6.1
Description	Androgen-dependent TFPI-regulating protein (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	p24.1
Chromosome location (bp)	11712054 - 11807046
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000111863 (version 83.38)
Entrez gene	84830
UniProt	Q96IZ2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96IZ2
Antibodypedia	ADTRP antibodies

PROTEIN BROWSER

ADTRP-001	ADTRP-002	ADTRP-004	ADTRP-007	ADTRP-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ADTRP-001 ENSP00000404416 ENST00000414691	Q96IZ2 [Direct mapping] Androgen-dependent TFPI-regulating protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Show all	GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] Show all	230 aa 26.8 kDa	No	6
ADTRP-002 ENSP00000368726 ENST00000379415	D6R9A9 [Direct mapping] Androgen-dependent TFPI-regulating protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	169 aa 19.6 kDa	No	4
ADTRP-004 ENSP00000229583 ENST00000229583	Q96IZ2 [Direct mapping] Androgen-dependent TFPI-regulating protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] Show all	248 aa 28.9 kDa	No	4
ADTRP-007 ENSP00000422927 ENST00000506810	A0A0E3D6L3 [Direct mapping] Androgen-dependent TFPI-regulating protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	168 aa 19.4 kDa	No	4
ADTRP-009 ENSP00000426507 ENST00000503285	H0YAA5 [Direct mapping] Androgen-dependent TFPI-regulating protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	116 aa 13.4 kDa	No	2

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.