Cell atlas - RHAG - The Human Protein Atlas

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RHAG

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	RHAG
Gene description	Rh-associated glycoprotein
Protein class	CD markers Disease related genes Potential drug targets Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Group enriched (HEL, K-562)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (HEL, K-562) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	RHAG (HGNC Symbol)
Synonyms	CD241, RH50A, SLC42A1
Description	Rh-associated glycoprotein (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is erythrocyte-specific and is thought to be part of a membrane channel that transports ammonium and carbon dioxide across the blood cell membrane. The encoded protein appears to interact with Rh blood group antigens and Rh30 polypeptides. Defects in this gene are a cause of regulator type Rh-null hemolytic anemia (RHN), or Rh-deficiency syndrome.[provided by RefSeq, Mar 2009]
Chromosome	6
Cytoband	p12.3
Chromosome location (bp)	49605158 - 49636839
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000112077 (version 83.38)
Entrez gene	6005
UniProt	Q02094 (UniProt - Evidence at protein level)
neXtProt	NX_Q02094
Antibodypedia	RHAG antibodies

PROTEIN BROWSER

RHAG-001	RHAG-201	RHAG-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RHAG-001 ENSP00000360217 ENST00000371175	Q02094 [Direct mapping] Ammonium transporter Rh type A Show all	CD markers Transporters Transporter channels and pores Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006873 [cellular ion homeostasis] GO:0008519 [ammonium transmembrane transporter activity] GO:0015670 [carbon dioxide transport] GO:0015696 [ammonium transport] GO:0015701 [bicarbonate transport] GO:0016020 [membrane] GO:0030506 [ankyrin binding] GO:0044281 [small molecule metabolic process] GO:0048821 [erythrocyte development] GO:0055085 [transmembrane transport] GO:0060586 [multicellular organismal iron ion homeostasis] GO:0072488 [ammonium transmembrane transport] Show all	409 aa 44.2 kDa	No	>9
RHAG-201 ENSP00000229810 ENST00000229810	A0A0A0MQS8 [Direct mapping] Ammonium transporter Rh type A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0008519 [ammonium transmembrane transporter activity] GO:0015696 [ammonium transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0072488 [ammonium transmembrane transport] Show all	410 aa 44.3 kDa	No	>9
RHAG-202 ENSP00000482984 ENST00000618248	A0A087WZZ4 [Direct mapping] Ammonium transporter Rh type A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0008519 [ammonium transmembrane transporter activity] GO:0015696 [ammonium transport] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0072488 [ammonium transmembrane transport] Show all	381 aa 40.9 kDa	No	>9

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.