Cell atlas - STK38 - The Human Protein Atlas

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STK38

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol

Human cell
	Cytosol

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GENERAL INFORMATION
Gene name	STK38
Gene description	Serine/threonine kinase 38
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA051324
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA051324	A-431	Cytosol
	HPA051324	U-2 OS	Cytosol
	HPA051324	U-251 MG	Cytosol

GENE INFORMATION
Gene name	STK38 (HGNC Symbol)
Synonyms	NDR
Description	Serine/threonine kinase 38 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cycle and apoptosis. This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Chromosome	6
Cytoband	p21.31
Chromosome location (bp)	36493892 - 36547470
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000112079 (version 83.38)
Entrez gene	11329
UniProt	Q15208 (UniProt - Evidence at protein level)
neXtProt	NX_Q15208
Antibodypedia	STK38 antibodies

PROTEIN BROWSER

STK38-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
STK38-001 ENSP00000229812 ENST00000229812	Q15208 [Direct mapping] Serine/threonine-protein kinase 38 A0A024RD18 [Target identity:100%; Query identity:100%] Serine/threonine kinase 38, isoform CRA_a Show all	Enzymes ENZYME proteins Transferases Kinases AGC Ser/Thr protein kinases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000287 [magnesium ion binding] GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006464 [cellular protein modification process] GO:0006468 [protein phosphorylation] GO:0031435 [mitogen-activated protein kinase kinase kinase binding] GO:0035556 [intracellular signal transduction] GO:0043407 [negative regulation of MAP kinase activity] GO:0070688 [MLL5-L complex] Show all	465 aa 54.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.