Expression of TSPO2 in cancer - Summary - The Human Protein Atlas

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TSPO2

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TSPO2
Gene description	Translocator protein 2
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (CACO-2)
HPA (normal tissue):	Tissue enriched (bone marrow)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA066996
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA066996

GENE INFORMATION
Gene name	TSPO2 (HGNC Symbol)
Synonyms	BZRPL1, dJ34B21.2
Description	Translocator protein 2 (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	p21.1
Chromosome location (bp)	41042554 - 41044337
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000112212 (version 83.38)
Entrez gene	222642
UniProt	Q5TGU0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q5TGU0
Antibodypedia	TSPO2 antibodies

PROTEIN BROWSER

TSPO2-001	TSPO2-002	TSPO2-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TSPO2-001 ENSP00000362255 ENST00000373161	Q5TGU0 [Direct mapping] Translocator protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006810 [transport] GO:0015485 [cholesterol binding] GO:0016021 [integral component of membrane] Show all	170 aa 19.1 kDa	No	4
TSPO2-002 ENSP00000419985 ENST00000470917	Q5TGU0 [Direct mapping] Translocator protein 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006810 [transport] GO:0015485 [cholesterol binding] GO:0016021 [integral component of membrane] Show all	170 aa 19.1 kDa	No	4
TSPO2-003 ENSP00000362252 ENST00000373158	Q5TGU0 [Direct mapping] Translocator protein 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0005783 [endoplasmic reticulum] GO:0005789 [endoplasmic reticulum membrane] GO:0006810 [transport] GO:0015485 [cholesterol binding] GO:0016021 [integral component of membrane] Show all	70 aa 8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.