Expression of FHL5 in cancer - Summary - The Human Protein Atlas

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FHL5

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	FHL5
Gene description	Four and a half LIM domains 5
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enhanced (testis)

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in glioma (favourable).
Glioma p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	FHL5 (HGNC Symbol)
Synonyms	ACT, dJ393D12.2, FLJ33049
Description	Four and a half LIM domains 5 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is coordinately expressed with activator of cAMP-responsive element modulator (CREM). It is associated with CREM and confers a powerful transcriptional activation function. CREM acts as a transcription factor essential for the differentiation of spermatids into mature spermatozoa. There are multiple polyadenylation sites found in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Dec 2009]
Chromosome	6
Cytoband	q16.1
Chromosome location (bp)	96562548 - 96616636
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000112214 (version 83.38)
Entrez gene	9457
UniProt	Q5TD97 (UniProt - Evidence at protein level)
neXtProt	NX_Q5TD97
Antibodypedia	FHL5 antibodies

PROTEIN BROWSER

FHL5-001	FHL5-002	FHL5-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FHL5-001 ENSP00000326022 ENST00000326771	Q5TD97 [Direct mapping] Four and a half LIM domains protein 5 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0003713 [transcription coactivator activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0008270 [zinc ion binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] Show all	284 aa 32.7 kDa	No	0
FHL5-002 ENSP00000396390 ENST00000450218	X6RED3 [Direct mapping] Four and a half LIM domains protein 5 Show all	Predicted intracellular proteins Show all	GO:0008270 [zinc ion binding] Show all	210 aa 24.6 kDa	No	0
FHL5-201 ENSP00000442357 ENST00000541107	Q5TD97 [Direct mapping] Four and a half LIM domains protein 5 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0008270 [zinc ion binding] Show all	284 aa 32.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.