Expression of AIM1 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

AIM1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	AIM1
Gene description	Absent in melanoma 1
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Tissue enhanced (placenta)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 3 antibodies. HPA030948 , HPA030949 , CAB026378
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

Urothelial cancer

STAINING SUMMARY

HPA030948	HPA030949	CAB026378

GENE INFORMATION
Gene name	AIM1 (HGNC Symbol)
Synonyms	CRYBG1, ST4
Description	Absent in melanoma 1 (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	q21
Chromosome location (bp)	106360808 - 106571978
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000112297 (version 83.38)
Entrez gene	202
UniProt	Q9Y4K1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y4K1
Antibodypedia	AIM1 antibodies

PROTEIN BROWSER

AIM1-001	AIM1-002	AIM1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AIM1-001 ENSP00000488010 ENST00000633556		Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		2131 aa 231.7 kDa	No	0
AIM1-002 ENSP00000391419 ENST00000457437	Q96QW7 [Direct mapping] Absent in melanoma 1 protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		316 aa 35.2 kDa	No	0
AIM1-201 ENSP00000358062 ENST00000369066	Q9Y4K1 [Direct mapping] Absent in melanoma 1 protein Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005575 [cellular_component] GO:0008150 [biological_process] GO:0030246 [carbohydrate binding] Show all	1723 aa 188.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.