Expression of C6orf62 in cancer - Summary - The Human Protein Atlas

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C6orf62

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C6orf62
Gene description	Chromosome 6 open reading frame 62
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Granular cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA030564 , HPA030566
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PROGNOSTIC SUMMARY
Prognostic marker in urothelial cancer (favourable), liver cancer (unfavourable) and ovarian cancer (favourable).
Urothelial cancer p<0.001 Liver cancer p<0.001 Ovarian cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA030564	HPA030566

GENE INFORMATION
Gene name	C6orf62 (HGNC Symbol)
Synonyms	DKFZP564G182, FLJ12619, XTP12
Description	Chromosome 6 open reading frame 62 (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	p22.3
Chromosome location (bp)	24704861 - 24720836
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000112308 (version 83.38)
Entrez gene	81688
UniProt	Q9GZU0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9GZU0
Antibodypedia	C6orf62 antibodies

PROTEIN BROWSER

C6orf62-001	C6orf62-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C6orf62-001 ENSP00000367359 ENST00000378119	Q9GZU0 [Direct mapping] Uncharacterized protein C6orf62 A0A024R026 [Target identity:100%; Query identity:100%] Chromosome 6 open reading frame 62, isoform CRA_a Show all	Predicted intracellular proteins Show all	GO:0003674 [molecular_function] GO:0005622 [intracellular] GO:0008150 [biological_process] Show all	229 aa 27.1 kDa	No	0
C6orf62-003 ENSP00000367342 ENST00000378102	Q9GZU0 [Direct mapping] Uncharacterized protein C6orf62 Show all	Predicted intracellular proteins Show all	GO:0003674 [molecular_function] GO:0005622 [intracellular] GO:0008150 [biological_process] Show all	200 aa 23.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.