Fields »
ABOUT
HELP
BLOG
FAM120B

GENERAL INFORMATION

Gene name

 FAM120B

Gene description

 Family with sequence similarity 120B

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Nuclear and cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 2 antibodies.
HPA037518 , HPA037519
SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in ovarian cancer (unfavourable) and pancreatic cancer (favourable).
Ovarian cancer p<0.001
Pancreatic cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA037518
HPA037519

GENE INFORMATION

Gene name

 FAM120B (HGNC Symbol)

Synonyms

 CCPG, KIAA1838, PGCC1

Description

 Family with sequence similarity 120B (HGNC Symbol)

Entrez gene summary

Chromosome

 6

Cytoband

 q27

Chromosome location (bp)

 170290703 - 170407065

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000112584 (version 83.38)

Entrez gene

 84498

UniProt

 Q96EK7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96EK7

Antibodypedia

 FAM120B antibodies

PROTEIN BROWSER
FAM120B-001
FAM120B-004
FAM120B-005
FAM120B-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FAM120B-001
ENSP00000417970
ENST00000476287
Q96EK7 [Direct mapping]
Constitutive coactivator of peroxisome proliferator-activated receptor gamma
Show all
   MEMSAT3 predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0030154 [cell differentiation]
Show all
 910 aa
103.8 kDa 		No 0
FAM120B-004
ENSP00000485793
ENST00000625626
Q96EK7 [Direct mapping]
Constitutive coactivator of peroxisome proliferator-activated receptor gamma
Show all
   MEMSAT3 predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0030154 [cell differentiation]
Show all
 242 aa
27.6 kDa 		No 0
FAM120B-005
ENSP00000485745
ENST00000630384
A0A0D9SEJ5 [Direct mapping]
Constitutive coactivator of peroxisome proliferator-activated receptor gamma
Show all
   MEMSAT3 predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 922 aa
105.2 kDa 		No 0
FAM120B-006
ENSP00000440125
ENST00000537664
F5GY05 [Direct mapping]
Constitutive coactivator of peroxisome proliferator-activated receptor gamma
Show all
   MEMSAT3 predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 933 aa
106.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.