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KIF20A

GENERAL INFORMATION

Gene name

 KIF20A

Gene description

 Kinesin family member 20A

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Tissue enhanced (testis)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Nuclear expression in varying fractions of cells in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 2 antibodies.
HPA036909 , HPA036910
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable), liver cancer (unfavourable), pancreatic cancer (unfavourable) and lung cancer (unfavourable).
Renal cancer p<0.001
Liver cancer p<0.001
Pancreatic cancer p<0.001
Lung cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA036909
HPA036910

GENE INFORMATION

Gene name

 KIF20A (HGNC Symbol)

Synonyms

 RAB6KIFL

Description

 Kinesin family member 20A (HGNC Symbol)

Entrez gene summary

Chromosome

 5

Cytoband

 q31.2

Chromosome location (bp)

 138178719 - 138187715

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000112984 (version 83.38)

Entrez gene

 10112

UniProt

 O95235 (UniProt - Evidence at protein level)

neXtProt

 NX_O95235

Antibodypedia

 KIF20A antibodies

PROTEIN BROWSER
KIF20A-001
KIF20A-002
KIF20A-004
KIF20A-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
KIF20A-001
ENSP00000378356
ENST00000394894
O95235 [Direct mapping]
Kinesin-like protein KIF20A
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000278 [mitotic cell cycle]
GO:0000281 [mitotic cytokinesis]
GO:0000910 [cytokinesis]
GO:0000920 [cell separation after cytokinesis]
GO:0001578 [microtubule bundle formation]
GO:0003777 [microtubule motor activity]
GO:0005215 [transporter activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005794 [Golgi apparatus]
GO:0005819 [spindle]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0007018 [microtubule-based movement]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0015031 [protein transport]
GO:0016192 [vesicle-mediated transport]
GO:0016887 [ATPase activity]
GO:0019901 [protein kinase binding]
GO:0030496 [midbody]
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 890 aa
100.3 kDa 		No 0
KIF20A-002
ENSP00000420880
ENST00000508792
O95235 [Direct mapping]
Kinesin-like protein KIF20A
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000278 [mitotic cell cycle]
GO:0000281 [mitotic cytokinesis]
GO:0000910 [cytokinesis]
GO:0000920 [cell separation after cytokinesis]
GO:0001578 [microtubule bundle formation]
GO:0003777 [microtubule motor activity]
GO:0005215 [transporter activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005654 [nucleoplasm]
GO:0005794 [Golgi apparatus]
GO:0005819 [spindle]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0007018 [microtubule-based movement]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0015031 [protein transport]
GO:0016192 [vesicle-mediated transport]
GO:0016887 [ATPase activity]
GO:0019901 [protein kinase binding]
GO:0030496 [midbody]
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 872 aa
98.1 kDa 		No 0
KIF20A-004
ENSP00000422928
ENST00000513276
D6R9E4 [Direct mapping]
Kinesin-like protein KIF20A
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0000910 [cytokinesis]
GO:0003777 [microtubule motor activity]
GO:0005524 [ATP binding]
GO:0005794 [Golgi apparatus]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0007018 [microtubule-based movement]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
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 159 aa
17.6 kDa 		No 0
KIF20A-005
ENSP00000424056
ENST00000504621
D6RBN1 [Direct mapping]
Kinesin-like protein
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0000910 [cytokinesis]
GO:0003777 [microtubule motor activity]
GO:0005524 [ATP binding]
GO:0005794 [Golgi apparatus]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0007018 [microtubule-based movement]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
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 225 aa
24.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.