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Cancer cells displayed strong cytoplasmic immunoreactivity with a granular staining pattern.
GENE INFORMATION
Gene name
HSPA9 (HGNC Symbol)
Synonyms
GRP75, HSPA9B, mot-2, mthsp75, PBP74
Description
Heat shock 70kDa protein 9 (mortalin) (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.[provided by RefSeq, May 2010]