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Most of the cancer tissues displayed moderate cytoplasmic and occasional nuclear positivity. Several renal, pancreatic and liver cancers were negative.
A majority of cancer tissues showed moderate cytoplasmic immunoreactivity.
GENE INFORMATION
Gene name
PPP2CA (HGNC Symbol)
Synonyms
PP2Calpha
Description
Protein phosphatase 2, catalytic subunit, alpha isozyme (HGNC Symbol)
Entrez gene summary
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008]