Tissue expression of HMGXB3 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	HMGXB3
Gene description	HMG box domain containing 3
Protein class	Plasma proteins Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (parathyroid gland)
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (parathyroid gland)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	HMGXB3 (HGNC Symbol)
Synonyms	HMGX3, KIAA0194, SMF
Description	HMG box domain containing 3 (HGNC Symbol)
Entrez gene summary	This gene is one of the non-canonical high mobility group (HMG) genes. The encoded protein contains an HMG-box domain found in DNA binding proteins such as transcription factors and chromosomal proteins. [provided by RefSeq, Aug 2011]
Chromosome	5
Cytoband	q32
Chromosome location (bp)	150000046 - 150053142
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000113716 (version 83.38)
Entrez gene	22993
UniProt	Q12766 (UniProt - Evidence at transcript level)
neXtProt	NX_Q12766
Antibodypedia	HMGXB3 antibodies

PROTEIN BROWSER

HMGXB3-001	HMGXB3-002	HMGXB3-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HMGXB3-001 ENSP00000421917 ENST00000502717	Q12766 [Direct mapping] HMG domain-containing protein 3 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Other all-alpha-helical DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005575 [cellular_component] GO:0005634 [nucleus] GO:0008150 [biological_process] GO:0016301 [kinase activity] GO:0016310 [phosphorylation] Show all	1292 aa 141.1 kDa	No	0
HMGXB3-002 ENSP00000422231 ENST00000503427	E9PEK0 [Direct mapping] HMG domain-containing protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		1260 aa 137.5 kDa	No	0
HMGXB3-201 ENSP00000479027 ENST00000613459	Q12766 [Direct mapping] HMG domain-containing protein 3 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Other all-alpha-helical DNA-binding domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005575 [cellular_component] GO:0005634 [nucleus] GO:0008150 [biological_process] GO:0016301 [kinase activity] GO:0016310 [phosphorylation] Show all	1538 aa 168.3 kDa	No	0