Expression of FAM162A in cancer - Summary - The Human Protein Atlas

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FAM162A

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM162A
Gene description	Family with sequence similarity 162, member A
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression with a granular pattern in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA035856
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PROGNOSTIC SUMMARY
Prognostic marker in urothelial cancer (favourable).
Urothelial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA035856

GENE INFORMATION
Gene name	FAM162A (HGNC Symbol)
Synonyms	C3orf28, E2IG5
Description	Family with sequence similarity 162, member A (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	q21.1
Chromosome location (bp)	122384176 - 122412334
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000114023 (version 83.38)
Entrez gene	26355
UniProt	Q96A26 (UniProt - Evidence at protein level)
neXtProt	NX_Q96A26
Antibodypedia	FAM162A antibodies

PROTEIN BROWSER

FAM162A-001	FAM162A-002	FAM162A-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM162A-001 ENSP00000419088 ENST00000477892	Q96A26 [Direct mapping] Protein FAM162A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0006919 [activation of cysteine-type endopeptidase activity involved in apoptotic process] GO:0006927 [transformed cell apoptotic process] GO:0016021 [integral component of membrane] GO:0043065 [positive regulation of apoptotic process] GO:0051402 [neuron apoptotic process] GO:0070062 [extracellular exosome] GO:0071456 [cellular response to hypoxia] GO:0090200 [positive regulation of release of cytochrome c from mitochondria] Show all	154 aa 17.3 kDa	No	1
FAM162A-002 ENSP00000419491 ENST00000469967	E9PH05 [Direct mapping] Protein FAM162A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0016021 [integral component of membrane] Show all	141 aa 16 kDa	No	1
FAM162A-003 ENSP00000232125 ENST00000232125	F8W7Q4 [Direct mapping] Protein FAM162A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0016021 [integral component of membrane] Show all	144 aa 16.5 kDa	No	1

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.