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Moderate to strong cytoplasmic staining was observed in most malignancies. Hepatocellular carcinomas, renal and prostate cancers were weakly staining or negative in several cases.
GENE INFORMATION
Gene name
FXR1
Synonyms
Description
Fragile X mental retardation, autosomal homolog 1 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
B4DXZ6 [Direct mapping] Fragile X mental retardation syndrome-related protein 1; cDNA FLJ58644, highly similar to Fragile X mental retardation syndrome-related protein 1
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Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014)