Expression of ABHD14A-ACY1 in cancer - Summary - The Human Protein Atlas

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ABHD14A-ACY1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ABHD14A-ACY1
Gene description	ABHD14A-ACY1 readthrough
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Not detected

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic positivity in renal tubules and hepatocytes.

ANTIBODY IHC RELIABILITY
Data reliability description	No internal RNA expression data available for correlation. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.
Reliability score	Uncertain based on 2 antibodies. HPA036174 , HPA036175
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA036174	HPA036175

GENE INFORMATION
Gene name	ABHD14A-ACY1
Synonyms
Description	ABHD14A-ACY1 readthrough (HGNC Symbol)
Entrez gene summary	This locus represents naturally occurring read-through transcription between the neighboring abhydrolase domain containing 14A (ABHD14A) and aminoacylase 1 (ACY1) genes on chromosome 3. The read-through transcript encodes a protein that shares sequence identity with the downstream gene product but its N-terminal region is distinct due to the use of an alternate start codon relative to the upstream gene. [provided by RefSeq, Oct 2015]
Chromosome	3
Cytoband	p21.2
Chromosome location (bp)	51975050 - 51989183
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000114786 (version 83.38)
Entrez gene	100526760
UniProt
neXtProt
Antibodypedia	ABHD14A-ACY1 antibodies

PROTEIN BROWSER

ABHD14A-ACY1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ABHD14A-ACY1-001 ENSP00000420487 ENST00000463937	C9JMV9 [Direct mapping] Protein ABHD14A-ACY1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0004046 [aminoacylase activity] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] GO:0006520 [cellular amino acid metabolic process] GO:0008152 [metabolic process] GO:0008237 [metallopeptidase activity] GO:0016787 [hydrolase activity] Show all	509 aa 56.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.