Cytoplasmic staining of varying intensity was displayed in tumor stroma. Most tumor cells were negative.
EFEMP1 (HGNC Symbol)
DHRD, FBLN3, FBNL, MTLV, S1-5
EGF containing fibulin-like extracellular matrix protein 1 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.[provided by RefSeq, Nov 2009]
Q12805 [Direct mapping] EGF-containing fibulin-like extracellular matrix protein 1
Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)