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PECR

GENERAL INFORMATION

Gene name

 PECR

Gene description

 Peroxisomal trans-2-enoyl-CoA reductase

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Cell line enhanced (RPTEC TERT1)
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Mainly cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 2 antibodies.
HPA021593 , HPA022539
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA021593
HPA022539

GENE INFORMATION

Gene name

 PECR (HGNC Symbol)

Synonyms

 HSA250303, SDR29C1, TERP

Description

 Peroxisomal trans-2-enoyl-CoA reductase (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 q35

Chromosome location (bp)

 215996329 - 216082955

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000115425 (version 83.38)

Entrez gene

 55825

UniProt

 Q9BY49 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9BY49

Antibodypedia

 PECR antibodies

PROTEIN BROWSER
PECR-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PECR-001
ENSP00000265322
ENST00000265322
Q9BY49 [Direct mapping]
Peroxisomal trans-2-enoyl-CoA reductase
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Enzymes
   ENZYME proteins
   Oxidoreductases
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005102 [receptor binding]
GO:0005739 [mitochondrion]
GO:0005777 [peroxisome]
GO:0005778 [peroxisomal membrane]
GO:0006633 [fatty acid biosynthetic process]
GO:0019166 [trans-2-enoyl-CoA reductase (NADPH) activity]
GO:0033306 [phytol metabolic process]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0055114 [oxidation-reduction process]
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 303 aa
32.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.