Cell atlas - IL1RL2 - The Human Protein Atlas

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IL1RL2

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	IL1RL2
Gene description	Interleukin 1 receptor-like 2
Protein class	Predicted membrane proteins Predicted secreted proteins
Predicted localization	Membrane,Secreted
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (A-431, ASC TERT1, HaCaT)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (A-431, ASC TERT1, HaCaT) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	IL1RL2 (HGNC Symbol)
Synonyms	IL1R-rp2, IL1RRP2
Description	Interleukin 1 receptor-like 2 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	q12.1
Chromosome location (bp)	102186973 - 102240002
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000115598 (version 83.38)
Entrez gene	8808
UniProt	Q9HB29 (UniProt - Evidence at protein level)
neXtProt	NX_Q9HB29
Antibodypedia	IL1RL2 antibodies

PROTEIN BROWSER

IL1RL2-001	IL1RL2-003	IL1RL2-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
IL1RL2-001 ENSP00000264257 ENST00000264257	Q9HB29 [Direct mapping] Interleukin-1 receptor-like 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0004908 [interleukin-1 receptor activity] GO:0004909 [interleukin-1, Type I, activating receptor activity] GO:0005515 [protein binding] GO:0005887 [integral component of plasma membrane] GO:0006954 [inflammatory response] GO:0006968 [cellular defense response] GO:0007165 [signal transduction] GO:0019221 [cytokine-mediated signaling pathway] GO:0032755 [positive regulation of interleukin-6 production] GO:0045087 [innate immune response] GO:0045582 [positive regulation of T cell differentiation] GO:0050727 [regulation of inflammatory response] GO:0070498 [interleukin-1-mediated signaling pathway] Show all	575 aa 65.4 kDa	Yes	1
IL1RL2-003 ENSP00000387611 ENST00000421464	C9K0I8 [Direct mapping] Interleukin-1 receptor-like 2 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005515 [protein binding] Show all	172 aa 19.5 kDa	Yes	0
IL1RL2-201 ENSP00000413348 ENST00000441515	Q9HB29 [Direct mapping] Interleukin-1 receptor-like 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0004908 [interleukin-1 receptor activity] GO:0004909 [interleukin-1, Type I, activating receptor activity] GO:0005515 [protein binding] GO:0005887 [integral component of plasma membrane] GO:0006954 [inflammatory response] GO:0006968 [cellular defense response] GO:0007165 [signal transduction] GO:0019221 [cytokine-mediated signaling pathway] GO:0045087 [innate immune response] GO:0070498 [interleukin-1-mediated signaling pathway] Show all	457 aa 51.7 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.