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Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

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Method

Validation

Method

Validation

Method

Validation

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Searches

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Cancer

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Tissue

Detectable

Cell line

Detectable

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Detectable

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ARID3A
  • TISSUE

  • premium

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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

ARID3A

Gene description

AT rich interactive domain 3A (BRIGHT-like)

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enhanced (placenta)
GTEx:Mixed
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Mainly nuclear expression, most abundant in placenta, testis and subsets of lymphoid cells.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Approved based on 1 antibody.
HPA004793
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
N/A
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (placenta)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

ARID3A (HGNC Symbol)

Synonyms

BRIGHT, DRIL1

Description

AT rich interactive domain 3A (BRIGHT-like) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA binding proteins. It was found by homology to the Drosophila dead ringer gene, which is important for normal embryogenesis. Other ARID family members have roles in embryonic patterning, cell lineage gene regulation, cell cycle control, transcriptional regulation, and possibly in chromatin structure modification. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

925781 - 975934

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000116017 (version 83.38)

Entrez gene

1820

UniProt

Q99856 (UniProt - Evidence at protein level)

neXtProt

NX_Q99856

Antibodypedia

ARID3A antibodies

PROTEIN BROWSER

ARID3A-001
ARID3A-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARID3A-001
ENSP00000263620
ENST00000263620
Q99856 [Direct mapping]
AT-rich interactive domain-containing protein 3A
Show all
Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0001228 [transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0042803 [protein homodimerization activity]
GO:0045121 [membrane raft]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
Show all
593 aa
62.9 kDa
No 0
ARID3A-005
ENSP00000464969
ENST00000587532
K7EJ04 [Direct mapping]
AT-rich interactive domain-containing protein 3A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
Show all
339 aa
35.5 kDa
No 0

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