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Few cases of endometrial, lung and liver cancers displayed moderate to strong cytoplasmic and occasional membranous positivity. Colorectal, breast, ovarian, pancreatic and stomach cancers showed weak to moderate positivity. Remaining cancer tissues were negative.
GENE INFORMATION
Gene name
QSOX1 (HGNC Symbol)
Synonyms
QSCN6
Description
Quiescin Q6 sulfhydryl oxidase 1 (HGNC Symbol)
Entrez gene summary
This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]