Expression of S100PBP in cancer - Summary - The Human Protein Atlas

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S100PBP

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	S100PBP
Gene description	S100P binding protein
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and nuclear expression in several tissues, including testis and brain.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA027242 , HPA027328
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable), head and neck cancer (favourable) and renal cancer (unfavourable).
Liver cancer p<0.001 Head and neck cancer p<0.001 Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA027242	HPA027328

GENE INFORMATION
Gene name	S100PBP (HGNC Symbol)
Synonyms	FLJ12903, S100PBPR
Description	S100P binding protein (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that was originally identified by its interaction with S100 calcium-binding protein P. Expression of this protein has been reported to be associated with pancreatic ductal adenocarcinoma. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]
Chromosome	1
Cytoband	p35.1
Chromosome location (bp)	32816767 - 32858879
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000116497 (version 83.38)
Entrez gene	64766
UniProt	Q96BU1 (UniProt - Evidence at protein level)
neXtProt	NX_Q96BU1
Antibodypedia	S100PBP antibodies

PROTEIN BROWSER

S100PBP-001	S100PBP-002	S100PBP-004	S100PBP-009	S100PBP-010	S100PBP-011	S100PBP-012	S100PBP-013

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
S100PBP-001 ENSP00000362574 ENST00000373475	Q96BU1 [Direct mapping] S100P-binding protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0048306 [calcium-dependent protein binding] Show all	408 aa 45.6 kDa	No	0
S100PBP-002 ENSP00000362575 ENST00000373476	Q96BU1 [Direct mapping] S100P-binding protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0048306 [calcium-dependent protein binding] Show all	408 aa 45.6 kDa	No	0
S100PBP-004 ENSP00000431432 ENST00000482212	E9PL86 [Direct mapping] S100P-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0048306 [calcium-dependent protein binding] Show all	146 aa 15.9 kDa	No	0
S100PBP-009 ENSP00000434933 ENST00000530710	E9PMK1 [Direct mapping] S100P-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0048306 [calcium-dependent protein binding] Show all	130 aa 14 kDa	No	0
S100PBP-010 ENSP00000431940 ENST00000526230	E9PIY5 [Direct mapping] S100P-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0048306 [calcium-dependent protein binding] Show all	120 aa 13.1 kDa	No	0
S100PBP-011 ENSP00000431921 ENST00000529027	E9PIZ7 [Direct mapping] S100P-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0048306 [calcium-dependent protein binding] Show all	41 aa 4.4 kDa	No	0
S100PBP-012 ENSP00000435856 ENST00000531256	E9PSA0 [Direct mapping] S100P-binding protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0048306 [calcium-dependent protein binding] Show all	171 aa 18.6 kDa	No	0
S100PBP-013 ENSP00000433456 ENST00000530552		Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		5 aa 0.6 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.