Expression of SCAMP3 in cancer - Summary - The Human Protein Atlas

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SCAMP3

TISSUE

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CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	SCAMP3
Gene description	Secretory carrier membrane protein 3
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable).
Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	SCAMP3 (HGNC Symbol)
Synonyms	C1orf3
Description	Secretory carrier membrane protein 3 (HGNC Symbol)
Entrez gene summary	This gene encodes an integral membrane protein that belongs to the secretory carrier membrane protein family. The encoded protein functions as a carrier to the cell surface in post-golgi recycling pathways. This protein is also involved in protein trafficking in endosomal pathways. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]
Chromosome	1
Cytoband	q22
Chromosome location (bp)	155255979 - 155262430
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000116521 (version 83.38)
Entrez gene	10067
UniProt	O14828 (UniProt - Evidence at protein level)
neXtProt	NX_O14828
Antibodypedia	SCAMP3 antibodies

PROTEIN BROWSER

SCAMP3-001	SCAMP3-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SCAMP3-001 ENSP00000307275 ENST00000302631	O14828 [Direct mapping] Secretory carrier-associated membrane protein 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000139 [Golgi membrane] GO:0006892 [post-Golgi vesicle-mediated transport] GO:0010033 [response to organic substance] GO:0015031 [protein transport] GO:0016021 [integral component of membrane] GO:0031625 [ubiquitin protein ligase binding] GO:0032526 [response to retinoic acid] GO:0070062 [extracellular exosome] Show all	347 aa 38.3 kDa	No	4
SCAMP3-002 ENSP00000347540 ENST00000355379	O14828 [Direct mapping] Secretory carrier-associated membrane protein 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0006892 [post-Golgi vesicle-mediated transport] GO:0015031 [protein transport] GO:0016021 [integral component of membrane] GO:0031625 [ubiquitin protein ligase binding] GO:0070062 [extracellular exosome] Show all	321 aa 35.2 kDa	No	4

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.