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Most malignant tissues showed weak to moderate nuclear positive. Strong staining was observed in malignant gliomas and carcinoids as well as several prostate cancers.
GENE INFORMATION
Gene name
RRAGC (HGNC Symbol)
Synonyms
FLJ13311, GTR2
Description
Ras-related GTP binding C (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the GTR/RAG GTP-binding protein family. The encoded protein is a monomeric guanine nucleotide-binding protein which forms a heterodimer with RRAGA and RRAGB and is primarily localized to the cytoplasm. The encoded protein promotes intracellular localization of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]