Tissue expression of HPCAL4 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	HPCAL4
Gene description	Hippocalcin like 4
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (cerebral cortex)
GTEx:	Group enriched (caudate, cerebellum, cerebral cortex, hippocampus, hypothalamus)
FANTOM5:	Group enriched (brain, caudate, cerebellum, hippocampus)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (cerebral cortex)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (caudate, cerebellum, cerebral cortex, hippocampus, hypothalamus)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (brain, caudate, cerebellum, hippocampus)

GENE INFORMATION
Gene name	HPCAL4 (HGNC Symbol)
Synonyms	DKFZp761G122, HLP4
Description	Hippocalcin like 4 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is highly similar to human hippocalcin protein and hippocalcin like-1 protein. It also has similarity to rat neural visinin-like Ca2+-binding protein-type 1 and 2 proteins. This encoded protein may be involved in the calcium-dependent regulation of rhodopsin phosphorylation. The transcript of this gene has multiple polyadenylation sites. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
Chromosome	1
Cytoband	p34.2
Chromosome location (bp)	39678648 - 39691689
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000116983 (version 83.38)
Entrez gene	51440
UniProt	Q9UM19 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UM19
Antibodypedia	HPCAL4 antibodies

PROTEIN BROWSER

HPCAL4-001	HPCAL4-201	HPCAL4-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HPCAL4-001 ENSP00000361935 ENST00000372844	Q9UM19 [Direct mapping] Hippocalcin-like protein 4 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005246 [calcium channel regulator activity] GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0007165 [signal transduction] GO:0007417 [central nervous system development] GO:0008022 [protein C-terminus binding] GO:0019904 [protein domain specific binding] Show all	191 aa 22.2 kDa	No	0
HPCAL4-201 ENSP00000484070 ENST00000612703	B4DGW9 [Direct mapping] Hippocalcin-like protein 4; cDNA FLJ50758, moderately similar to Hippocalcin-like protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005246 [calcium channel regulator activity] GO:0005509 [calcium ion binding] GO:0007165 [signal transduction] Show all	119 aa 13.9 kDa	No	0
HPCAL4-202 ENSP00000481834 ENST00000617690	Q9UM19 [Direct mapping] Hippocalcin-like protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0007165 [signal transduction] GO:0007417 [central nervous system development] Show all	191 aa 22.2 kDa	No	0