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Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

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Score

Score

Score

Antibodies

Column

 
 
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MYCL
  • TISSUE

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PATHOLOGY ATLAS

GENE/PROTEIN

Dictionary

GENERAL INFORMATION

Gene name

MYCL

Gene description

V-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog

Protein class

Cancer-related genes
Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Expressed in all
HPA (cell line):Group enriched (U-266/70, U-266/84)
HPA (normal tissue):Tissue enhanced (skin)

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

Pending cancer tissue analysis.

PROGNOSTIC SUMMARY

Prognostic marker in lung cancer (favourable).
Lung cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Pending cancer tissue analysis


STAINING SUMMARY

 

GENE INFORMATION

Gene name

MYCL (HGNC Symbol)

Synonyms

bHLHe38, LMYC, MYCL1

Description

V-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog (HGNC Symbol)

Entrez gene summary

Chromosome

1

Cytoband

p34.2

Chromosome location (bp)

39895426 - 39902256

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000116990 (version 83.38)

Entrez gene

4610

UniProt

P12524 (UniProt - Evidence at protein level)

neXtProt

NX_P12524

Antibodypedia

MYCL antibodies

PROTEIN BROWSER

MYCL-001
MYCL-002
MYCL-003
MYCL-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MYCL-001
ENSP00000380494
ENST00000397332
P12524 [Direct mapping]
Protein L-Myc
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Amplifications
   COSMIC Somatic Mutations
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0045607 [regulation of auditory receptor cell differentiation]
GO:0046983 [protein dimerization activity]
Show all
394 aa
43.2 kDa
No 0
MYCL-002
ENSP00000361902
ENST00000372815
P12524 [Direct mapping]
Protein L-Myc
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Amplifications
   COSMIC Somatic Mutations
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046983 [protein dimerization activity]
Show all
236 aa
24.7 kDa
No 0
MYCL-003
ENSP00000434375
ENST00000450953
E9PQS5 [Direct mapping]
Protein L-Myc
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Amplifications
   COSMIC Somatic Mutations
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
100 aa
11.1 kDa
No 0
MYCL-004
ENSP00000361903
ENST00000372816
P12524 [Direct mapping]
Protein L-Myc
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Amplifications
   COSMIC Somatic Mutations
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046983 [protein dimerization activity]
Show all
364 aa
40.3 kDa
No 0

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