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Malignant cells generally showed weak cytoplasmic staining or were negative. A majority of malignant gliomas and liver cancers were moderately stained.
GENE INFORMATION
Gene name
SIPA1L2 (HGNC Symbol)
Synonyms
KIAA1389
Description
Signal-induced proliferation-associated 1 like 2 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the signal-induced proliferation-associated 1 like family. Members of this family contain a GTPase activating domain, a PDZ domain and a C-terminal coiled-coil domain with a leucine zipper. A similar protein in rat acts as a GTPases for the small GTPase Rap. [provided by RefSeq, Sep 2015]