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SSX2IP

GENERAL INFORMATION

Gene name

 SSX2IP

Gene description

 Synovial sarcoma, X breakpoint 2 interacting protein

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (testis)
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression, including membrane positivity in a few tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA027306
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 SSX2IP

Synonyms

Description

 Synovial sarcoma, X breakpoint 2 interacting protein (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein that binds the cancer-testis antigen Synovial Sarcoma X breakpoint 2 protein. The encoded protein may regulate the activity of Synovial Sarcoma X breakpoint 2 protein in malignant cells. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Oct 2009]

Chromosome

 1

Cytoband

 p22.3

Chromosome location (bp)

 84643707 - 84690803

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000117155 (version 83.38)

Entrez gene

 117178

UniProt

 Q9Y2D8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y2D8

Antibodypedia

 SSX2IP antibodies

PROTEIN BROWSER
SSX2IP-001
SSX2IP-007
SSX2IP-008
SSX2IP-009
SSX2IP-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SSX2IP-001
ENSP00000340279
ENST00000342203
Q9Y2D8 [Direct mapping]
Afadin- and alpha-actinin-binding protein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005912 [adherens junction]
GO:0005913 [cell-cell adherens junction]
GO:0007155 [cell adhesion]
GO:0019904 [protein domain specific binding]
GO:0031252 [cell leading edge]
GO:0034451 [centriolar satellite]
GO:0035020 [regulation of Rac protein signal transduction]
GO:0035735 [intraciliary transport involved in cilium morphogenesis]
GO:0036064 [ciliary basal body]
GO:0042384 [cilium assembly]
GO:0043234 [protein complex]
GO:0051297 [centrosome organization]
GO:2000145 [regulation of cell motility]
Show all
 614 aa
71.2 kDa 		No 0
SSX2IP-007
ENSP00000416067
ENST00000422026
C9JIX7 [Direct mapping]
Afadin- and alpha-actinin-binding protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 180 aa
20.7 kDa 		No 0
SSX2IP-008
ENSP00000474480
ENST00000605755
Q9Y2D8 [Direct mapping]
Afadin- and alpha-actinin-binding protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0034451 [centriolar satellite]
GO:0035735 [intraciliary transport involved in cilium morphogenesis]
GO:0036064 [ciliary basal body]
GO:0042384 [cilium assembly]
GO:0043234 [protein complex]
GO:0051297 [centrosome organization]
Show all
 587 aa
68.3 kDa 		No 0
SSX2IP-009
ENSP00000473763
ENST00000603677
S4R2Y6 [Direct mapping]
Afadin- and alpha-actinin-binding protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 87 aa
9.7 kDa 		No 0
SSX2IP-201
ENSP00000412781
ENST00000437941
Q9Y2D8 [Direct mapping]
Afadin- and alpha-actinin-binding protein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0034451 [centriolar satellite]
GO:0035735 [intraciliary transport involved in cilium morphogenesis]
GO:0036064 [ciliary basal body]
GO:0042384 [cilium assembly]
GO:0043234 [protein complex]
GO:0051297 [centrosome organization]
Show all
 587 aa
68.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.