Expression of MTFR1L in cancer - Summary - The Human Protein Atlas

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MTFR1L

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	MTFR1L
Gene description	Mitochondrial fission regulator 1-like
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	15
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA027124 , HPA027130
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable) and endometrial cancer (favourable).
Renal cancer p<0.001 Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA027124	HPA027130

GENE INFORMATION
Gene name	MTFR1L (HGNC Symbol)
Synonyms	FAM54B
Description	Mitochondrial fission regulator 1-like (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p36.11
Chromosome location (bp)	25818640 - 25832942
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000117640 (version 83.38)
Entrez gene	56181
UniProt	Q9H019 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H019
Antibodypedia	MTFR1L antibodies

PROTEIN BROWSER

MTFR1L-001	MTFR1L-002	MTFR1L-003	MTFR1L-004	MTFR1L-005	MTFR1L-007	MTFR1L-011	MTFR1L-013	MTFR1L-014	MTFR1L-015	MTFR1L-016	MTFR1L-017	MTFR1L-019	MTFR1L-021	MTFR1L-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MTFR1L-001 ENSP00000363419 ENST00000374301	Q9H019 [Direct mapping] Mitochondrial fission regulator 1-like Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000266 [mitochondrial fission] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0009060 [aerobic respiration] Show all	292 aa 32 kDa	No	0
MTFR1L-002 ENSP00000435461 ENST00000474295	Q9H019 [Direct mapping] Mitochondrial fission regulator 1-like Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000266 [mitochondrial fission] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0009060 [aerobic respiration] Show all	205 aa 22.8 kDa	No	0
MTFR1L-003 ENSP00000363426 ENST00000374307	Q9H019 [Direct mapping] Mitochondrial fission regulator 1-like Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000266 [mitochondrial fission] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0009060 [aerobic respiration] Show all	280 aa 30.8 kDa	No	0
MTFR1L-004 ENSP00000363418 ENST00000374300	Q9H019 [Direct mapping] Mitochondrial fission regulator 1-like Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000266 [mitochondrial fission] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0009060 [aerobic respiration] Show all	292 aa 32 kDa	No	0
MTFR1L-005 ENSP00000434751 ENST00000466284	Q9H019 [Direct mapping] Mitochondrial fission regulator 1-like Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000266 [mitochondrial fission] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0009060 [aerobic respiration] Show all	205 aa 22.8 kDa	No	0
MTFR1L-007 ENSP00000390841 ENST00000424294	C9JF50 [Direct mapping] Mitochondrial fission regulator 1-like Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000266 [mitochondrial fission] GO:0005739 [mitochondrion] GO:0009060 [aerobic respiration] Show all	152 aa 16.7 kDa	No	0
MTFR1L-011 ENSP00000435193 ENST00000524618	E9PLD2 [Direct mapping] Mitochondrial fission regulator 1-like Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000266 [mitochondrial fission] GO:0005739 [mitochondrion] GO:0009060 [aerobic respiration] Show all	195 aa 21.2 kDa	No	0
MTFR1L-013 ENSP00000432719 ENST00000472643	E9PPF9 [Direct mapping] Mitochondrial fission regulator 1-like Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000266 [mitochondrial fission] GO:0005739 [mitochondrion] GO:0009060 [aerobic respiration] Show all	160 aa 17.1 kDa	No	0
MTFR1L-014 ENSP00000434773 ENST00000533762	E9PNJ0 [Direct mapping] Mitochondrial fission regulator 1-like Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000266 [mitochondrial fission] GO:0005739 [mitochondrion] GO:0009060 [aerobic respiration] Show all	13 aa 1.4 kDa	No	0
MTFR1L-015 ENSP00000434038 ENST00000529116	E9PSD6 [Direct mapping] Mitochondrial fission regulator 1-like Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000266 [mitochondrial fission] GO:0005739 [mitochondrion] GO:0009060 [aerobic respiration] Show all	115 aa 12.8 kDa	No	0
MTFR1L-016 ENSP00000436954 ENST00000488327	E9PPQ0 [Direct mapping] Mitochondrial fission regulator 1-like Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000266 [mitochondrial fission] GO:0005739 [mitochondrion] GO:0009060 [aerobic respiration] Show all	53 aa 5.8 kDa	No	0
MTFR1L-017 ENSP00000432227 ENST00000526894	E9PRK5 [Direct mapping] Mitochondrial fission regulator 1-like Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000266 [mitochondrial fission] GO:0005739 [mitochondrion] GO:0009060 [aerobic respiration] Show all	182 aa 20 kDa	No	0
MTFR1L-019 ENSP00000434120 ENST00000525713	E9PRW1 [Direct mapping] Mitochondrial fission regulator 1-like Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000266 [mitochondrial fission] GO:0005739 [mitochondrion] GO:0009060 [aerobic respiration] Show all	110 aa 12.2 kDa	No	0
MTFR1L-021 ENSP00000431278 ENST00000526158	E9PLU1 [Direct mapping] Mitochondrial fission regulator 1-like Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000266 [mitochondrial fission] GO:0005739 [mitochondrion] GO:0009060 [aerobic respiration] Show all	170 aa 18.5 kDa	No	0
MTFR1L-201 ENSP00000363421 ENST00000374303	Q9H019 [Direct mapping] Mitochondrial fission regulator 1-like Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000266 [mitochondrial fission] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0009060 [aerobic respiration] Show all	292 aa 32 kDa	No	0

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