Expression of ADGB in cancer - Summary - The Human Protein Atlas

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ADGB

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ADGB
Gene description	Androglobin
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Cell line enriched (HDLM-2)
HPA (normal tissue):	Group enriched (fallopian tube, testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ciliary expression in fallopian tube, endometrium and respiratory epithelium.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Supported based on 1 antibody. HPA036340
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA036340

GENE INFORMATION
Gene name	ADGB (HGNC Symbol)
Synonyms	C6orf103, CAPN16, dJ408K24.1, FLJ23121
Description	Androglobin (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	q24.3
Chromosome location (bp)	146598965 - 146815462
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000118492 (version 83.38)
Entrez gene	79747
UniProt	Q8N7X0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8N7X0
Antibodypedia	ADGB antibodies

PROTEIN BROWSER

ADGB-002	ADGB-004	ADGB-005	ADGB-008	ADGB-009	ADGB-011	ADGB-013

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ADGB-002 ENSP00000356460 ENST00000367490	H0Y334 [Direct mapping] Androglobin Show all	Predicted intracellular proteins Show all	GO:0004198 [calcium-dependent cysteine-type endopeptidase activity] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	625 aa 71.5 kDa	No	0
ADGB-004 ENSP00000356459 ENST00000367489	H0Y333 [Direct mapping] Androglobin Show all	Predicted intracellular proteins Show all	GO:0004198 [calcium-dependent cysteine-type endopeptidase activity] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	112 aa 13.4 kDa	No	0
ADGB-005 ENSP00000323839 ENST00000326916	F8W7W4 [Direct mapping] Androglobin Show all	Predicted intracellular proteins Show all	GO:0004198 [calcium-dependent cysteine-type endopeptidase activity] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	259 aa 28.9 kDa	No	0
ADGB-008 ENSP00000430834 ENST00000473647	H0YC38 [Direct mapping] Androglobin Show all	Predicted intracellular proteins Show all	GO:0004198 [calcium-dependent cysteine-type endopeptidase activity] GO:0005622 [intracellular] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	71 aa 8.4 kDa	No	0
ADGB-009 ENSP00000381036 ENST00000397944	Q8N7X0 [Direct mapping] Androglobin Show all	Enzymes Peptidases Cysteine-type peptidases Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0004198 [calcium-dependent cysteine-type endopeptidase activity] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] GO:0019825 [oxygen binding] GO:0020037 [heme binding] Show all	1667 aa 189.7 kDa	No	0
ADGB-011 ENSP00000428035 ENST00000522242	E5RFN4 [Direct mapping] Androglobin Show all	Predicted intracellular proteins Show all	GO:0004198 [calcium-dependent cysteine-type endopeptidase activity] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	178 aa 20.4 kDa	No	0
ADGB-013 ENSP00000427779 ENST00000470716	E5RG76 [Direct mapping] Androglobin Show all	Predicted intracellular proteins Show all	GO:0004198 [calcium-dependent cysteine-type endopeptidase activity] GO:0005737 [cytoplasm] GO:0006508 [proteolysis] Show all	141 aa 15.5 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.