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Mainly localized to the plasma membrane & nucleoplasm. In addition localized to the cytosol & vesicles.
Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category
Expressed in all
Protein evidence
Evidence at protein level
Main location
Localized to the Nucleoplasm (supported), Plasma membrane (supported)
Additional location
In addition localized to the Vesicles (supported), Cytosol (supported)
Cell lines sorted after organ of phenotypic resemblance.
Cell lines sorted after biological source for establishment.
Cell lines sorted after the cell line category according to Cellosaurus.
Cell lines sorted on descending RNA expression.
Cell lines sorted alphabetically.
HUMAN CELLS
Summary
Mainly localized to the plasma membrane & nucleoplasm. In addition localized to the cytosol & vesicles.
Caution: Based on antibodies targeting proteins from multiple genes.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq, Jul 2008]