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PHF19

GENERAL INFORMATION

Gene name

 PHF19

Gene description

 PHD finger protein 19

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 8
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Mixed

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable), liver cancer (unfavourable) and endometrial cancer (unfavourable).
Renal cancer p<0.001
Liver cancer p<0.001
Endometrial cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 PHF19 (HGNC Symbol)

Synonyms

 DKFZP727G051, MTF2L1, PCL3, TDRD19B

Description

 PHD finger protein 19 (HGNC Symbol)

Entrez gene summary

Chromosome

 9

Cytoband

 q33.2

Chromosome location (bp)

 120855652 - 120894896

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000119403 (version 83.38)

Entrez gene

 26147

UniProt

 Q5T6S3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q5T6S3

Antibodypedia

 PHF19 antibodies

PROTEIN BROWSER
PHF19-001
PHF19-003
PHF19-005
PHF19-006
PHF19-009
PHF19-010
PHF19-201
PHF19-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PHF19-001
ENSP00000363003
ENST00000373896
Q5T6S3 [Direct mapping]
PHD finger protein 19
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0016568 [chromatin modification]
GO:0035064 [methylated histone binding]
GO:0035098 [ESC/E(Z) complex]
GO:0040029 [regulation of gene expression, epigenetic]
GO:0045814 [negative regulation of gene expression, epigenetic]
GO:0061087 [positive regulation of histone H3-K27 methylation]
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 580 aa
65.6 kDa 		No 0
PHF19-003
ENSP00000310372
ENST00000312189
Q5T6S3 [Direct mapping]
PHD finger protein 19
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0016568 [chromatin modification]
GO:0035064 [methylated histone binding]
GO:0035098 [ESC/E(Z) complex]
GO:0040029 [regulation of gene expression, epigenetic]
GO:0045814 [negative regulation of gene expression, epigenetic]
GO:0061087 [positive regulation of histone H3-K27 methylation]
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 207 aa
22.5 kDa 		No 0
PHF19-005
ENSP00000397935
ENST00000456291
X6RER8 [Direct mapping]
PHD finger protein 19
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 107 aa
12 kDa 		No 0
PHF19-006
ENSP00000408479
ENST00000436309
B0QZ72 [Direct mapping]
PHD finger protein 19
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
GO:0008270 [zinc ion binding]
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 166 aa
18.3 kDa 		No 0
PHF19-009
ENSP00000404655
ENST00000439674
B0QZ51 [Direct mapping]
PHD finger protein 19
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 60 aa
7.4 kDa 		No 0
PHF19-010
ENSP00000395938
ENST00000453868
B0QZ50 [Direct mapping]
PHD finger protein 19
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 173 aa
20.2 kDa 		No 0
PHF19-201
ENSP00000407433
ENST00000419155
F5H8K3 [Direct mapping]
PHD finger protein 19
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 371 aa
42.2 kDa 		No 0
PHF19-202
ENSP00000483946
ENST00000616568
A0A087X169 [Direct mapping]
PHD finger protein 19
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0005515 [protein binding]
GO:0008270 [zinc ion binding]
GO:0019827 [stem cell population maintenance]
GO:0048863 [stem cell differentiation]
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 599 aa
67.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.