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Several stomach cancers, few cases of ovarian, lung, pancreatic cancers showed moderate to strong granular cytoplasmic positivity. Most remaining malignant tissues were weakly stained or negative.
GENE INFORMATION
Gene name
NEK6 (HGNC Symbol)
Synonyms
SID6-1512
Description
NIMA-related kinase 6 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a kinase required for progression through the metaphase portion of mitosis. Inhibition of the encoded protein can lead to apoptosis. This protein also can enhance tumorigenesis by suppressing tumor cell senescence. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Enzymes ENZYME proteins Transferases Kinases NEK Ser/Thr protein kinases Transporters Transporter channels and pores MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Enzymes ENZYME proteins Transferases Kinases NEK Ser/Thr protein kinases Transporters Transporter channels and pores MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Enzymes ENZYME proteins Transferases Kinases NEK Ser/Thr protein kinases Transporters Transporter channels and pores MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Enzymes ENZYME proteins Transferases Kinases NEK Ser/Thr protein kinases Transporters Transporter channels and pores MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Enzymes ENZYME proteins Transferases Kinases NEK Ser/Thr protein kinases Transporters Transporter channels and pores MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Enzymes ENZYME proteins Transferases Kinases NEK Ser/Thr protein kinases Transporters Transporter channels and pores MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Enzymes ENZYME proteins Transferases Kinases NEK Ser/Thr protein kinases Transporters Transporter channels and pores MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)