Expression of C19orf25 in cancer - Summary - The Human Protein Atlas

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C19orf25

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C19orf25
Gene description	Chromosome 19 open reading frame 25
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	10
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Nuclear and cytoplasmic expression in a few tissues, mainly in squamous epithelia.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA050270
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable), endometrial cancer (favourable), pancreatic cancer (favourable) and liver cancer (unfavourable).
Renal cancer p<0.001 Endometrial cancer p<0.001 Pancreatic cancer p<0.001 Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA050270

GENE INFORMATION
Gene name	C19orf25 (HGNC Symbol)
Synonyms	FLJ36666
Description	Chromosome 19 open reading frame 25 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	1461143 - 1479556
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000119559 (version 83.38)
Entrez gene	148223
UniProt	Q9UFG5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UFG5
Antibodypedia	C19orf25 antibodies

PROTEIN BROWSER

C19orf25-001	C19orf25-002	C19orf25-003	C19orf25-004	C19orf25-005	C19orf25-008	C19orf25-009	C19orf25-010	C19orf25-011	C19orf25-012

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C19orf25-001 ENSP00000397394 ENST00000436106	Q9UFG5 [Direct mapping] UPF0449 protein C19orf25 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	118 aa 12.9 kDa	No	0
C19orf25-002 ENSP00000389254 ENST00000427685	E7EP72 [Direct mapping] UPF0449 protein C19orf25 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		158 aa 17.1 kDa	No	0
C19orf25-003 ENSP00000468688 ENST00000585675	Q9UFG5 [Direct mapping] UPF0449 protein C19orf25 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	118 aa 12.9 kDa	No	0
C19orf25-004 ENSP00000465469 ENST00000588871	K7EK56 [Direct mapping] UPF0449 protein C19orf25 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		160 aa 17.1 kDa	No	0
C19orf25-005 ENSP00000466283 ENST00000588849	K7ELZ1 [Direct mapping] UPF0449 protein C19orf25 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		86 aa 9.3 kDa	No	0
C19orf25-008 ENSP00000468000 ENST00000588427	K7EQW1 [Direct mapping] UPF0449 protein C19orf25 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		71 aa 7.5 kDa	No	0
C19orf25-009 ENSP00000467861 ENST00000592872	Q9UFG5 [Direct mapping] UPF0449 protein C19orf25 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	118 aa 12.9 kDa	No	0
C19orf25-010 ENSP00000466372 ENST00000586564	Q9UFG5 [Direct mapping] UPF0449 protein C19orf25 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	118 aa 12.9 kDa	No	0
C19orf25-011 ENSP00000468064 ENST00000590621	K7ER12 [Direct mapping] UPF0449 protein C19orf25 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		42 aa 4.5 kDa	No	0
C19orf25-012 ENSP00000478936 ENST00000591027	A0A087WUU5 [Direct mapping] UPF0449 protein C19orf25 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		78 aa 8.5 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.