Expression of YLPM1 in cancer - Summary - The Human Protein Atlas

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YLPM1

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	YLPM1
Gene description	YLP motif containing 1
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic, membranous and nuclear expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA048070
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA048070

GENE INFORMATION
Gene name	YLPM1 (HGNC Symbol)
Synonyms	C14orf170, PPP1R169, ZAP
Description	YLP motif containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q24.3
Chromosome location (bp)	74763366 - 74859435
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000119596 (version 83.38)
Entrez gene	56252
UniProt	P49750 (UniProt - Evidence at protein level)
neXtProt	NX_P49750
Antibodypedia	YLPM1 antibodies

PROTEIN BROWSER

YLPM1-001	YLPM1-003	YLPM1-008	YLPM1-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
YLPM1-001 ENSP00000324463 ENST00000325680	P49750 [Direct mapping] YLP motif-containing protein 1 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0008150 [biological_process] GO:0016607 [nuclear speck] GO:0032204 [regulation of telomere maintenance] GO:0044822 [poly(A) RNA binding] Show all	2146 aa 241.6 kDa	No	0
YLPM1-003 ENSP00000448367 ENST00000547879	H0YI23 [Direct mapping] YLP motif-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] Show all	466 aa 54.1 kDa	No	0
YLPM1-008 ENSP00000447921 ENST00000552421	F8VU51 [Direct mapping] YLP motif-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] Show all	1440 aa 160.7 kDa	No	0
YLPM1-010 ENSP00000476212 ENST00000554107	U3KQT9 [Direct mapping] YLP motif-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] Show all	110 aa 12.5 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.