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Most malignant cells displayed moderate to strong cytoplasmic immunoreactivity with a granular pattern. Several renal, liver and skin cancers were however negative.
GENE INFORMATION
Gene name
SLIRP (HGNC Symbol)
Synonyms
C14orf156, DC50
Description
SRA stem-loop interacting RNA binding protein (HGNC Symbol)
Entrez gene summary
Steroid receptor RNA activator (SRA, or SRA1; MIM 603819) is a complex RNA molecule containing multiple stable stem-loop structures that functions in coactivation of nuclear receptors. SLIRP interacts with stem-loop structure-7 of SRA (STR7) and modulates nuclear receptor transactivation (Hatchell et al., 2006 [PubMed 16762838]).[supplied by OMIM, Mar 2008]