Fields »
ABOUT
HELP
BLOG
AFTPH

GENERAL INFORMATION

Gene name

 AFTPH

Gene description

 Aftiphilin

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Granular cytoplasmic expression most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 2 antibodies.
HPA034990 , HPA034991
SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable), urothelial cancer (favourable) and stomach cancer (favourable).
Renal cancer p<0.001
Urothelial cancer p<0.001
Stomach cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA034990
HPA034991

GENE INFORMATION

Gene name

 AFTPH (HGNC Symbol)

Synonyms

 FLJ20080, FLJ23793, MGC33965, Nbla10388

Description

 Aftiphilin (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 p14

Chromosome location (bp)

 64524305 - 64593005

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000119844 (version 83.38)

Entrez gene

 54812

UniProt

 Q6ULP2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q6ULP2

Antibodypedia

 AFTPH antibodies

PROTEIN BROWSER
AFTPH-001
AFTPH-002
AFTPH-003
AFTPH-201
AFTPH-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
AFTPH-001
ENSP00000387071
ENST00000409933
Q6ULP2 [Direct mapping]
Aftiphilin
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0015031 [protein transport]
GO:0030121 [AP-1 adaptor complex]
GO:0030276 [clathrin binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0046907 [intracellular transport]
Show all
 936 aa
102.1 kDa 		No 0
AFTPH-002
ENSP00000386913
ENST00000409183
B8ZZI9 [Direct mapping]
Aftiphilin
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
GO:0043231 [intracellular membrane-bounded organelle]
Show all
 592 aa
64.2 kDa 		No 0
AFTPH-003
ENSP00000238856
ENST00000238856
Q6ULP2 [Direct mapping]
Aftiphilin
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0015031 [protein transport]
GO:0030121 [AP-1 adaptor complex]
GO:0030276 [clathrin binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0046907 [intracellular transport]
Show all
 909 aa
99.5 kDa 		No 0
AFTPH-201
ENSP00000238855
ENST00000238855
Q6ULP2 [Direct mapping]
Aftiphilin
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005794 [Golgi apparatus]
GO:0005829 [cytosol]
GO:0015031 [protein transport]
GO:0030121 [AP-1 adaptor complex]
GO:0030276 [clathrin binding]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0046907 [intracellular transport]
Show all
 936 aa
102.1 kDa 		No 0
AFTPH-202
ENSP00000397726
ENST00000422803
A0A0A0MSN6 [Direct mapping]
Aftiphilin
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 138 aa
15 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.