Cell atlas - CUTC - The Human Protein Atlas

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CUTC

TISSUE

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CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm

Human cell
	Cytosol
	Nucleoplasm

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GENERAL INFORMATION
Gene name	CUTC
Gene description	CutC copper transporter
Protein class	Predicted intracellular proteins Transporters
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the cytosol & nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (supported), Cytosol (supported)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA038619
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the cytosol & nucleoplasm.

Main location

Nucleoplasm (supported), Cytosol (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA038619	A-431	Nucleoplasm
	HPA038619	A-431	Cytosol
	HPA038619	U-2 OS	Cytosol
	HPA038619	U-251 MG	Nucleoplasm
			Nucleoli	Intensity
			Cytosol

GENE INFORMATION
Gene name	CUTC (HGNC Symbol)
Synonyms	CGI-32
Description	CutC copper transporter (HGNC Symbol)
Entrez gene summary	Members of the CUT family of copper transporters are associated with copper homeostasis and are involved in the uptake, storage, delivery, and efflux of copper (Gupta et al., 1995 [PubMed 7635807]; Li et al., 2005 [PubMed 16182249]).[supplied by OMIM, Mar 2008]
Chromosome	10
Cytoband	q24.2
Chromosome location (bp)	99702558 - 99756134
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000119929 (version 83.38)
Entrez gene	51076
UniProt	Q9NTM9 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NTM9
Antibodypedia	CUTC antibodies

PROTEIN BROWSER

CUTC-001	CUTC-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CUTC-001 ENSP00000359507 ENST00000370476	Q9NTM9 [Direct mapping] Copper homeostasis protein cutC homolog Show all	Transporters Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005507 [copper ion binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0006825 [copper ion transport] GO:0034220 [ion transmembrane transport] GO:0051262 [protein tetramerization] GO:0055070 [copper ion homeostasis] GO:0055085 [transmembrane transport] Show all	273 aa 29.3 kDa	No	0
CUTC-003 ENSP00000359503 ENST00000370472	Q5TCZ7 [Direct mapping] Copper homeostasis protein cutC homolog Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005507 [copper ion binding] GO:0055070 [copper ion homeostasis] Show all	144 aa 15.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.