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HOXB1

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GENERAL INFORMATION

Gene name

 HOXB1

Gene description

 Homeobox B1

Protein class

 Disease related genes
Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Not detected

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 HOXB1 (HGNC Symbol)

Synonyms

 HOX2, HOX2I

Description

 Homeobox B1 (HGNC Symbol)

Entrez gene summary

 This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17. [provided by RefSeq, Jul 2008]

Chromosome

 17

Cytoband

 q21.32

Chromosome location (bp)

 48528526 - 48530997

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000120094 (version 83.38)

Entrez gene

 3211

UniProt

 P14653 (UniProt - Evidence at protein level)

neXtProt

 NX_P14653

Antibodypedia

 HOXB1 antibodies

PROTEIN BROWSER
HOXB1-001
HOXB1-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
HOXB1-001
ENSP00000355140
ENST00000239174
P14653 [Direct mapping]
Homeobox protein Hox-B1
Show all
Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Disease related genes
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007275 [multicellular organismal development]
GO:0007389 [pattern specification process]
GO:0009653 [anatomical structure morphogenesis]
GO:0009952 [anterior/posterior pattern specification]
GO:0019904 [protein domain specific binding]
GO:0021546 [rhombomere development]
GO:0021570 [rhombomere 4 development]
GO:0021571 [rhombomere 5 development]
GO:0021612 [facial nerve structural organization]
GO:0021754 [facial nucleus development]
GO:0043565 [sequence-specific DNA binding]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0048646 [anatomical structure formation involved in morphogenesis]
GO:0048704 [embryonic skeletal system morphogenesis]
Show all
 301 aa
32.2 kDa 		No 0
HOXB1-002
ENSP00000459066
ENST00000577092
P14653 [Direct mapping]
Homeobox protein Hox-B1
Show all
Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Disease related genes
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007275 [multicellular organismal development]
GO:0007389 [pattern specification process]
GO:0019904 [protein domain specific binding]
Show all
 232 aa
24.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.