Expression of MSANTD2 in cancer - Summary - The Human Protein Atlas

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MSANTD2

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	MSANTD2
Gene description	Myb/SANT-like DNA-binding domain containing 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous granular cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.
Reliability score	Approved based on 2 antibodies. HPA038694 , HPA038695
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable) and urothelial cancer (favourable).
Renal cancer p<0.001 Urothelial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA038694	HPA038695

GENE INFORMATION
Gene name	MSANTD2 (HGNC Symbol)
Synonyms	C11orf61, FLJ23342
Description	Myb/SANT-like DNA-binding domain containing 2 (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	q24.2
Chromosome location (bp)	124766498 - 124800673
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000120458 (version 83.38)
Entrez gene	79684
UniProt	Q6P1R3 (UniProt - Evidence at protein level)
neXtProt	NX_Q6P1R3
Antibodypedia	MSANTD2 antibodies

PROTEIN BROWSER

MSANTD2-001	MSANTD2-002	MSANTD2-003	MSANTD2-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MSANTD2-001 ENSP00000239614 ENST00000239614	Q6P1R3 [Direct mapping] Myb/SANT-like DNA-binding domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		507 aa 55.4 kDa	No	0
MSANTD2-002 ENSP00000364118 ENST00000374979	Q6P1R3 [Direct mapping] Myb/SANT-like DNA-binding domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		559 aa 61.3 kDa	No	0
MSANTD2-003 ENSP00000431707 ENST00000524950	B4E1M0 [Direct mapping] Myb/SANT-like DNA-binding domain-containing protein 2; cDNA FLJ54230 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		179 aa 17.8 kDa	No	0
MSANTD2-004 ENSP00000435705 ENST00000526629	Q6P1R3 [Direct mapping] Myb/SANT-like DNA-binding domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		329 aa 38 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.