Expression of SLC10A7 in cancer - Summary - The Human Protein Atlas

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SLC10A7

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	SLC10A7
Gene description	Solute carrier family 10, member 7
Protein class	Predicted intracellular proteins Predicted membrane proteins Transporters
Predicted localization	Intracellular,Membrane
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA039996
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA039996

GENE INFORMATION
Gene name	SLC10A7 (HGNC Symbol)
Synonyms	C4orf13, DKFZp313H0531, DKFZp566M114, DKFZp779O2438, MGC25043
Description	Solute carrier family 10, member 7 (HGNC Symbol)
Entrez gene summary
Chromosome	4
Cytoband	q31.22
Chromosome location (bp)	146253975 - 146521964
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000120519 (version 83.38)
Entrez gene	84068
UniProt	Q0GE19 (UniProt - Evidence at transcript level)
neXtProt	NX_Q0GE19
Antibodypedia	SLC10A7 antibodies

PROTEIN BROWSER

SLC10A7-001	SLC10A7-002	SLC10A7-003	SLC10A7-004	SLC10A7-005	SLC10A7-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC10A7-001 ENSP00000334594 ENST00000335472	Q0GE19 [Direct mapping] Sodium/bile acid cotransporter 7 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006814 [sodium ion transport] GO:0015293 [symporter activity] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] Show all	340 aa 37.4 kDa	No	7
SLC10A7-002 ENSP00000411297 ENST00000432059	Q0GE19 [Direct mapping] Sodium/bile acid cotransporter 7 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006814 [sodium ion transport] GO:0015293 [symporter activity] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] Show all	327 aa 36.1 kDa	No	6
SLC10A7-003 ENSP00000422577 ENST00000502607	Q0GE19 [Direct mapping] Sodium/bile acid cotransporter 7 Show all	Transporters Electrochemical Potential-driven transporters MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006814 [sodium ion transport] GO:0015293 [symporter activity] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] Show all	64 aa 7 kDa	No	0
SLC10A7-004 ENSP00000377623 ENST00000394059	Q0GE19 [Direct mapping] Sodium/bile acid cotransporter 7 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006814 [sodium ion transport] GO:0015293 [symporter activity] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] Show all	159 aa 17.3 kDa	No	2
SLC10A7-005 ENSP00000421603 ENST00000511374	Q0GE19 [Direct mapping] Sodium/bile acid cotransporter 7 Show all	Transporters Electrochemical Potential-driven transporters MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006814 [sodium ion transport] GO:0015293 [symporter activity] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] Show all	85 aa 9.4 kDa	No	0
SLC10A7-009 ENSP00000421275 ENST00000507030	Q0GE19 [Direct mapping] Sodium/bile acid cotransporter 7 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006814 [sodium ion transport] GO:0015293 [symporter activity] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] Show all	358 aa 39.5 kDa	No	7

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The Human Protein Atlas

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