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Cell line enhanced (A-431, HL-60, Karpas-707, NB-4, U-266/84)
HPA (normal tissue):
Tissue enriched (testis)
Protein evidence
Evidence at transcript level
ANTIBODY IHC RELIABILITY
Reliability score
Pending cancer tissue analysis.
PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all
RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed
PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY
GENE INFORMATION
Gene name
SOHLH2 (HGNC Symbol)
Synonyms
bHLHe81, FLJ20449, SPATA28, TEB1
Description
Spermatogenesis and oogenesis specific basic helix-loop-helix 2 (HGNC Symbol)
Entrez gene summary
This gene encodes one of testis-specific transcription factors which are essential for spermatogenesis, oogenesis and folliculogenesis. This gene is located on chromosome 13. The proteins encoded by this gene and another testis-specific transcription factor, SOHLH1, can form heterodimers, in addition to homodimers. There is a read-through locus (GeneID: 100526761) that shares sequence identity with this gene and the upstream CCDC169 (GeneID: 728591). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]