Expression of GLT8D2 in cancer - Summary - The Human Protein Atlas

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GLT8D2

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GLT8D2
Gene description	Glycosyltransferase 8 domain containing 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (ASC TERT1, BJ hTERT+)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and/or membranous expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA026904
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable), cervical cancer (unfavourable) and stomach cancer (unfavourable).
Renal cancer p<0.001 Cervical cancer p<0.001 Stomach cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA026904

GENE INFORMATION
Gene name	GLT8D2 (HGNC Symbol)
Synonyms	FLJ31494
Description	Glycosyltransferase 8 domain containing 2 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q23.3
Chromosome location (bp)	103988984 - 104064183
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000120820 (version 83.38)
Entrez gene	83468
UniProt	Q9H1C3 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9H1C3
Antibodypedia	GLT8D2 antibodies

PROTEIN BROWSER

GLT8D2-001	GLT8D2-002	GLT8D2-003	GLT8D2-004	GLT8D2-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GLT8D2-001 ENSP00000447450 ENST00000548660	Q9H1C3 [Direct mapping] Glycosyltransferase 8 domain-containing protein 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SignalP predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000271 [polysaccharide biosynthetic process] GO:0005794 [Golgi apparatus] GO:0016021 [integral component of membrane] GO:0016757 [transferase activity, transferring glycosyl groups] Show all	349 aa 40 kDa	No	0
GLT8D2-002 ENSP00000354053 ENST00000360814	Q9H1C3 [Direct mapping] Glycosyltransferase 8 domain-containing protein 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SignalP predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000271 [polysaccharide biosynthetic process] GO:0005794 [Golgi apparatus] GO:0016021 [integral component of membrane] GO:0016757 [transferase activity, transferring glycosyl groups] Show all	349 aa 40 kDa	No	0
GLT8D2-003 ENSP00000449750 ENST00000546436	Q9H1C3 [Direct mapping] Glycosyltransferase 8 domain-containing protein 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SignalP predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000271 [polysaccharide biosynthetic process] GO:0005794 [Golgi apparatus] GO:0016021 [integral component of membrane] GO:0016757 [transferase activity, transferring glycosyl groups] Show all	349 aa 40 kDa	No	0
GLT8D2-004 ENSP00000446810 ENST00000546851	F8VZP2 [Direct mapping] Glycosyltransferase 8 domain-containing protein 2 Show all	TMHMM predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		66 aa 7.6 kDa	No	0
GLT8D2-005 ENSP00000448065 ENST00000547583	F8VU19 [Direct mapping] Glycosyltransferase 8 domain-containing protein 2 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SignalP predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	83 aa 9.2 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.