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TEX14

GENERAL INFORMATION

Gene name

 TEX14

Gene description

 Testis expressed 14

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Cell line enhanced (HDLM-2, Karpas-707, MCF7)
HPA (normal tissue):Tissue enriched (testis)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 TEX14 (HGNC Symbol)

Synonyms

 CT113

Description

 Testis expressed 14 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is necessary for intercellular bridges in germ cells, which are required for spermatogenesis. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011]

Chromosome

 17

Cytoband

 q22

Chromosome location (bp)

 58556678 - 58692055

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000121101 (version 83.38)

Entrez gene

 56155

UniProt

 Q8IWB6 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8IWB6

Antibodypedia

 TEX14 antibodies

PROTEIN BROWSER
TEX14-001
TEX14-003
TEX14-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TEX14-001
ENSP00000374584
ENST00000389934
Q8IWB6 [Direct mapping]
Inactive serine/threonine-protein kinase TEX14
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Enzymes
   Kinases
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0000776 [kinetochore]
GO:0000777 [condensed chromosome kinetochore]
GO:0004672 [protein kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005623 [cell]
GO:0005737 [cytoplasm]
GO:0006468 [protein phosphorylation]
GO:0007094 [mitotic spindle assembly checkpoint]
GO:0007140 [male meiosis]
GO:0008608 [attachment of spindle microtubules to kinetochore]
GO:0019901 [protein kinase binding]
GO:0030496 [midbody]
GO:0043063 [intercellular bridge organization]
GO:0045171 [intercellular bridge]
GO:0051301 [cell division]
GO:0051306 [mitotic sister chromatid separation]
GO:0070062 [extracellular exosome]
Show all
 1491 aa
167.1 kDa 		No 0
TEX14-003
ENSP00000240361
ENST00000240361
Q8IWB6 [Direct mapping]
Inactive serine/threonine-protein kinase TEX14
Show all
Enzymes
   Kinases
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0000776 [kinetochore]
GO:0000777 [condensed chromosome kinetochore]
GO:0004672 [protein kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005623 [cell]
GO:0005737 [cytoplasm]
GO:0006468 [protein phosphorylation]
GO:0007094 [mitotic spindle assembly checkpoint]
GO:0007140 [male meiosis]
GO:0008608 [attachment of spindle microtubules to kinetochore]
GO:0019901 [protein kinase binding]
GO:0030496 [midbody]
GO:0032091 [negative regulation of protein binding]
GO:0032466 [negative regulation of cytokinesis]
GO:0043063 [intercellular bridge organization]
GO:0045171 [intercellular bridge]
GO:0051301 [cell division]
GO:0051306 [mitotic sister chromatid separation]
GO:0070062 [extracellular exosome]
Show all
 1497 aa
167.9 kDa 		No 0
TEX14-004
ENSP00000268910
ENST00000349033
Q8IWB6 [Direct mapping]
Inactive serine/threonine-protein kinase TEX14
Show all
Enzymes
   Kinases
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0000776 [kinetochore]
GO:0000777 [condensed chromosome kinetochore]
GO:0004672 [protein kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005623 [cell]
GO:0005737 [cytoplasm]
GO:0006468 [protein phosphorylation]
GO:0007094 [mitotic spindle assembly checkpoint]
GO:0007140 [male meiosis]
GO:0008608 [attachment of spindle microtubules to kinetochore]
GO:0019901 [protein kinase binding]
GO:0030496 [midbody]
GO:0043063 [intercellular bridge organization]
GO:0045171 [intercellular bridge]
GO:0051301 [cell division]
GO:0051306 [mitotic sister chromatid separation]
GO:0070062 [extracellular exosome]
Show all
 1451 aa
162.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.