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TSHZ3

GENERAL INFORMATION

Gene name

 TSHZ3

Gene description

 Teashirt zinc finger homeobox 3

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Cell line enhanced (RH-30, U-138 MG)
HPA (normal tissue):Mixed

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Ubiquitous nuclear expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA008834
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable).
Renal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA008834

GENE INFORMATION

Gene name

 TSHZ3 (HGNC Symbol)

Synonyms

 KIAA1474, TSH3, ZNF537

Description

 Teashirt zinc finger homeobox 3 (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 q12

Chromosome location (bp)

 31274945 - 31349547

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000121297 (version 83.38)

Entrez gene

 57616

UniProt

 Q63HK5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q63HK5

Antibodypedia

 TSHZ3 antibodies

PROTEIN BROWSER
TSHZ3-001
TSHZ3-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TSHZ3-001
ENSP00000240587
ENST00000240587
Q63HK5 [Direct mapping]
Teashirt homolog 3
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Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0002087 [regulation of respiratory gaseous exchange by neurological system process]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0007275 [multicellular organismal development]
GO:0030426 [growth cone]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
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 1081 aa
118.6 kDa 		No 0
TSHZ3-002
ENSP00000475613
ENST00000558569
U3KQ78 [Direct mapping]
Teashirt homolog 3
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 33 aa
4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.