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TMEM39B

GENERAL INFORMATION

Gene name

 TMEM39B

Gene description

 Transmembrane protein 39B

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 2 antibodies.
HPA040191 , HPA040224
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 TMEM39B (HGNC Symbol)

Synonyms

 FLJ10315

Description

 Transmembrane protein 39B (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 p35.2

Chromosome location (bp)

 32072031 - 32102866

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000121775 (version 83.38)

Entrez gene

 55116

UniProt

 Q9GZU3 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9GZU3

Antibodypedia

 TMEM39B antibodies

PROTEIN BROWSER
TMEM39B-001
TMEM39B-009

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TMEM39B-001
ENSP00000338165
ENST00000336294
Q9GZU3 [Direct mapping]
Transmembrane protein 39B
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   8TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002230 [positive regulation of defense response to virus by host]
GO:0016021 [integral component of membrane]
GO:0098779 [mitophagy in response to mitochondrial depolarization]
Show all
 492 aa
56.3 kDa 		No 8
TMEM39B-009
ENSP00000414616
ENST00000438825
Q5VVU5 [Direct mapping]
Transmembrane protein 39B
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   5TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
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GO:0016021 [integral component of membrane]
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 192 aa
21.5 kDa 		No 5

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.