Tissue expression of TBX22 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	TBX22
Gene description	T-box 22
Protein class	Disease related genes Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (testis, thyroid gland)
GTEx:	Group enriched (testis, thyroid gland)
FANTOM5:	Tissue enriched (testis)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (testis, thyroid gland)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (testis, thyroid gland)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	TBX22 (HGNC Symbol)
Synonyms	CLPA, CPX
Description	T-box 22 (HGNC Symbol)
Entrez gene summary	This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome	X
Cytoband	q21.1
Chromosome location (bp)	80014756 - 80031769
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000122145 (version 83.38)
Entrez gene	50945
UniProt	Q9Y458 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y458
Antibodypedia	TBX22 antibodies

PROTEIN BROWSER

TBX22-001	TBX22-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TBX22-001 ENSP00000362390 ENST00000373294	Q9Y458 [Direct mapping] T-box transcription factor TBX22 Show all	Predicted intracellular proteins Transcription factors Immunoglobulin fold Disease related genes Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007275 [multicellular organismal development] GO:0045892 [negative regulation of transcription, DNA-templated] Show all	520 aa 57.9 kDa	No	0
TBX22-201 ENSP00000362393 ENST00000373296	Q9Y458 [Direct mapping] T-box transcription factor TBX22 Show all	Predicted intracellular proteins Transcription factors Immunoglobulin fold Disease related genes Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0007275 [multicellular organismal development] GO:0045892 [negative regulation of transcription, DNA-templated] Show all	520 aa 57.9 kDa	No	0