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Most malignant cells displayed weak nuclear staining with additional cytoplasmic positivity or were negative. A majority of non-Hodgkins lymphomas and ovarian cancers as well as a few hepatocellular carcinomas, malignant gliomas, breast, prostate and pancreatic cancers were moderately stained.
GENE INFORMATION
Gene name
MYOG (HGNC Symbol)
Synonyms
bHLHc3, MYF4
Description
Myogenin (myogenic factor 4) (HGNC Symbol)
Entrez gene summary
Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix (HLH) proteins. It is essential for the development of functional skeletal muscle. [provided by RefSeq, Jul 2008]