Expression of LRRC39 in cancer - Summary - The Human Protein Atlas

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LRRC39

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	LRRC39
Gene description	Leucine rich repeat containing 39
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (SK-MEL-30)
HPA (normal tissue):	Group enriched (heart muscle, skeletal muscle)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

RNA-data suggests selective expression in heart and skeletal muscle.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA028443 , HPA029724
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA028443	HPA029724

GENE INFORMATION
Gene name	LRRC39 (HGNC Symbol)
Synonyms	MGC14816
Description	Leucine rich repeat containing 39 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p21.2
Chromosome location (bp)	100148449 - 100178273
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000122477 (version 83.38)
Entrez gene	127495
UniProt	Q96DD0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96DD0
Antibodypedia	LRRC39 antibodies

PROTEIN BROWSER

LRRC39-001	LRRC39-002	LRRC39-201	LRRC39-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LRRC39-001 ENSP00000359156 ENST00000370137	Q96DD0 [Direct mapping] Leucine-rich repeat-containing protein 39 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	335 aa 38.8 kDa	No	0
LRRC39-002 ENSP00000359157 ENST00000370138	Q96DD0 [Direct mapping] Leucine-rich repeat-containing protein 39 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	339 aa 39.4 kDa	No	0
LRRC39-201 ENSP00000344470 ENST00000342895	Q96DD0 [Direct mapping] Leucine-rich repeat-containing protein 39 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] Show all	335 aa 38.8 kDa	No	0
LRRC39-202 ENSP00000480740 ENST00000620882	Q96DD0 [Direct mapping] Leucine-rich repeat-containing protein 39 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	339 aa 39.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.